Overview of IGF-1
IGF-1 (Insulin-like growth factor 1), also called Somatomedin 1, IGF-I, IGFI, IGF1, IGF-IA, and mechano growth factor, was named for its close resemblance to proinsulin. Buy igf-1 des is encoded by the IGF1 gene. IGF-1 is comprised of 70 amino acids with a molecular weight of 7649 Da. It’s amino acid sequence is GPETLCGAEL VDALQFVCGD RGFYFNKPTGYGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA. It is known as an important peptide for growth throughout the lifecycle of mammals.
How it Works IGF-1 is most commonly generated by the liver in response to production of growth hormone by the pituitary gland, but it can be produced in the fetus and other tissues for localized purposes. It has been shown to play a critical role in cell growth, apoptosis (programmed cell death), cell division, and the transfer of glucose across cell membranes. Interestingly, it is found to have the opposite effect on adipose (fat) tissue. IGF-1 inhibits the growth of adipose tissue while restricting glucose transport which encourages the body to burn adipose tissue for energy.
About IGF-1 LR3 Long arginine 3-IGF-1, also called Long r3 IGF-1, LR3 IGF, IGF1 LR3, LongArg3 IGF- 1, is a synthetic version of IGF-1. It differs from IGF-1 by having an additional 13 amino acids at its N-terminus making it 83 amino acids. There is also a substitution in the corresponding IGF-1 third position of glutamic acid for an arginine. It has a molecular weight of 9105.4 Da. It’s amino acid sequence is MFPAMPLSSL FVNGPRTLCG AELVDALQFVCGDRGFYFNK PTGYGSSSRR APQTGIV DEC CFRSCDLRRL EMYCAPLKPA KSA. The difference in chemical composition makes the ability to bind to IGF proteins less efficient. The result is a 2.5 times increase in potency. Additionally, it has a prolonged half-life of 20-30 hours. buy igf des